Supporting research across the full spectrum of medical sciences in Scotland

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“The available funds allowed 14 small awards and eight large projects to be supported, following further scrutiny and support from the National Scientific Advisory Committee.”

Tenovus Tayside has had another successful year in 2015/16.

Applications received and Project reports

The Committee has been very fortunate to have had a total sum of just over £734,000 available for supporting research projects. This was raised through donations from a number of local Trusts, legacies and fundraising events. During the year 40 small grant applications and 21 larger applications were received and all were fully peer-reviewed by the Local Scientific Advisory Committee.

The available funds allowed 14 small awards and eight large projects to be supported, following further scrutiny and support from the National Scientific Advisory Committee. Seven final reports, all deemed highly satisfactory, were received.

Income generation and events

The Events Committee, led by Mrs Gloria Burns, has been very active throughout the year, arranging a number of functions. A particular highlight was a musical evening held in Dundee High School at which outstanding performances were given by pupils from the school, members of Dundee Symphony Orchestra, and a number of very talented musicians from Ninewells Hospital and Medical School. A golf outing, bridge lunches, and the annual dinner, as always a highly popular event, raised £7,443.

One very successful development was a scientific symposium for our local lay supporters to hear more about some of the research projects that have benefited from Tenovus funding – a number of these have had major international impact and have resulted in substantial further research funding from other major Research Councils and Charities. This opportunity gave supporters the chance to meet some of the very enthusiastic clinical and nonclinical scientific research staff in person, which was much appreciated by both the supporters and the research staff.

Committee and Thanks

As always, the work of Tenovus depends on the enthusiastic support of our Committee Members, including our Scientific Advisory Committee. In this regard, we have been very sorry to lose Professor Sara Marshall, who has moved from Dundee to London; however, her role of Chair of the Scientific Advisory Committee and member of our full Committee has been taken by Professor Tim Hales, who has already stepped very ably into her shoes.

Professor John Connell, Chairman

Tayside Committee

AS AT 31 MARCH 2016

Lady Fiona Fraser

Mrs P Dunn, Mr N J Robertson

Professor J M Connell

Mr A F McDonald

Mr J M C Wilson

Mrs G Burns, Mr M Etherington, Professor T Hales, Professor P W Howie, Mr D J Smith, Mr D J Young


Professor T Hales, Professor C Lang, Dr S Rocha, Dr F Williams


Mrs G Burns


Mrs A Anderson, Mrs D Beattie, Mrs M Boyle, Dr B Coupar, Dr J Forsyth, Mrs C Fowlie, Mrs M Graham, Mrs A Gray, Mrs U Horspool, Mrs A Mackay, Dr J McEwen, Dr A Morris,
Mrs M Munro, Mrs N Smith, Dr C Taig, Mrs D Willliamson

Pilot Projects 2015/16 (Grants up to £15,000)

Dr Clare Clarke How does medication use affect levels of physical activity in older people?

Dr Matthew Holden Mapping the genetic diversity of the pathogen, Staphylococcus aureus, directly from the skin of eczema patients

Dr Craig Heath How common is epilepsy in those attending opioid replacement programmes and does attendance at such programmes improve medication adherence and reduce use of unscheduled care, serious harm or death?

Dr Helge C Dorfmueller Towards the discovery of chemical tools to prevent human infection caused by Streptococcus pyogenes bacteria

Dr Christos Pliotas Tackling Antimicrobial Resistance (AMR) by controlled manipulation of cell membrane channel pores -molecular gating studies lead to effective drug targeting

Dr Soo-Youn Choi Unravelling novel regulatory networks controlling immune responses and lymphomagenesis

Dr Michael Nevels A new strategy of fighting human Cytomegalovirus infections

Dr Lee Kang Targeting cardiac fibrosis and insulin resistance to treat heart failure

Dr Weihua Meng An association study linking e-health records and DNA chips to identify genes for diabetic retinopathy

Dr Greg Findlay Using chemical tools to develop novel approaches to tissue replacement therapy

Dr Fiona Bull Does inhibition of c-Src kinase enable morphine to produce a long lasting reduction in persistent pain?

Dr Maurice AM van Steensel Understanding kidney cancer by studying a rare genetic disease

Mr Aidan Rose Investigating cancer promoting mechanisms in skin cancer

Dr Victoria Sherwood Investigations into a novel drug target for skin cancer treatment

Large Grants 2015/16 (Up to £100,000)

Dr Samira Bell Using linkage of hospital datasets to find out whether adjusting the timing of operations and x-ray scans using dye can reduce the risk of kidney failure

Mrs E Jane Macaskill Pre-surgical imaging and biological study of patients with hormone positive early breast cancer: can we predict those with resistant disease?

Dr R Petty Characterisation of a new subgroup of oesophageal cancers that could be treated with targeted therapies thereby avoiding chemotherapy and improving clinical outcomes

Dr Faisel Khan A preliminary study in patients to see how inflammation contributes to heart and blood vessel disease

Dr Daniel Morales Angiotensin converting enzyme inhibitors in asthma: pharmacoepidemiology studies using linked UK health data

Dr Yogesh Kulathu How does the MINDY family of enzymes protect us from ageing and neurodegeneration?

Dr Maurice AM van Steensel A new function for an ancient protein reveals causes of kidney cancer

Dr Mark Larance Does the immune system mediate the beneficial effects of intermittent fasting?

©2016 Tenovus Scotland